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🧪 Experimental Design

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Trial Search

Current Search Criteria:

Intervention: placebo to tocilizumab SC

Found 11 matching trials

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

PHASE3

This randomized, double-blind, parallel group study compares the efficacy a...

Status

Completed

Location

Multiple Locations

Start Date

2010-09

Trial ID

NCT01194414

Treatments Being Tested

tocilizumab SC tocilizumab IV placebo to tocilizumab SC placebo to tocilizumab IV Disease-modifying antirheumatic drugs (DMARDs)

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

PHASE3

Primary Objective: To assess, in the same study, the safety of sarilumab a...

Status

Completed

Location

Investigational Site Number 840152

Start Date

2013-03

Trial ID

NCT01768572

Treatments Being Tested

sarilumab SAR153191 (REGN88)tocilizumab hydroxychloroquine methotrexate sulfasalazine leflunomide subcutaneous placebo intravenous placebo

An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA)

PHASE3

This multicenter, randomized, double-blind, placebo-controlled, parallel-gr...

Status

Completed

Location

Univ of Calif., Los Angeles; Rheumatology

Start Date

2013-07-22

Trial ID

NCT01791153

Treatments Being Tested

Tocilizumab Prednisone Tocilizumab Placebo Prednisone Placebo Corticosteroids Methotrexate

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

PHASE4

This randomized, parallel-group study will assess the efficacy and safety o...

Status

Terminated

Location

Multiple Locations

Start Date

2011-05

Trial ID

NCT01283971

Treatments Being Tested

tocilizumab [RoActemra/Actemra]adalimumab placebo to tocilizumab placebo to adalimumab methotrexate folate

A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX

PHASE3

This randomized, multicenter, double-blind, parallel group study will evalu...

Status

Completed

Location

Pinnacle Research Group; Llc, Central

Start Date

2013-11-07

Trial ID

NCT01855789

Treatments Being Tested

Tocilizumab (TCZ)Methotrexate (MTX)Placebo (PBO)

A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)

PHASE3

This study will assess the efficacy and safety of tocilizumab compared with...

Status

Completed

Location

TriWest Research Associates, LLC

Start Date

2015-11-20

Trial ID

NCT02453256

Treatments Being Tested

Placebo Tocilizumab

Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

PHASE2

The purpose of this study is to evaluate the safety, efficacy, pharmacokine...

Status

Completed

Location

166

Start Date

2010-11

Trial ID

NCT01242488

Treatments Being Tested

CDP6038 CDP6038 CDP6038 Tocilizumab (Actemra or RoActemra)CDP6038 CDP6038 CDP6038 Placebo sc Placebo sc Placebo iv

A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma

PHASE2

The purpose of this study is to find out whether giving a single dose of to...

Status

Recruiting

Location

Beverly Hills Cancer Center (BHCC)

Start Date

2026-06-30

Trial ID

NCT07589634

Treatments Being Tested

Ramantamig Tocilizumab Placebo

A Study of RoActemra/Actemra (Tocilizumab) Given Subcutaneously in Combination With Traditional DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

PHASE3

This randomized, parallel-group, placebo-controlled, multicenter study will...

Status

Completed

Location

Multiple Locations

Start Date

2011-03

Trial ID

NCT01232569

Treatments Being Tested

Tocilizumab 162 mg Placebo

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

PHASE3

This is a randomized, double-blind, multi-center, parallel-group study to e...

Status

Completed

Location

The First Affiliated Hospital of Baotou Medical College

Start Date

2017-08-02

Trial ID

NCT03155347

Treatments Being Tested

Tocilizumab MTX Placebo Matched to MTX Placebo Matched to Tocilizumab

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